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Since 2007 GENVIP has published more than 430 publications

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RESPIRATORY SYNCYTIAL VIRUS-ASSOCIATED ACUTE LOWER RESPIRATORY INFECTIONS IN CHILDREN WITH BRONCHOPULMONARY DYSPLASIA: SYSTEMATIC REVIEW AND META-ANALYSIS
Chaw PS, Hua L, Cunningham S, Campbell H, Mikolajczyk R, Nair H; RESCEU Investigators (Nair H, Campbell H, Shi T, Zhang S, Li Y, Hua L, Openshaw P, Wedzicha J, Falsey A, Miller M, Bont L, Pollard A, Molero E, Martinon-Torres F, Heikkinen T, Meijer A, Fischer TK, van den Berge M, Giaquinto C, Mikolajczyk R, Chaw PS, Gallichan S, Kieffer A, Demont C, Hackett J, Cai B, Knirsch C, Leach A, Stoszek S, Cheret A, Gavart S, Aerssens J, Fuentes R, Rosen B)
Journal:
Publicación independiente
Impact factor
Year:
2019
Doi:
PLASMA LIPID PROFILES DISCRIMINATE BACTERIAL FROM VIRAL INFECTION IN FEBRILE CHILDREN
Xinzhu Wang, Ruud Nijman, Stephane Camuzeaux, Caroline Sands, Heather Jackson, Myrsini Kaforou, Marieke Emonts, Jethro A. Herberg, Ian Maconochie, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Michiel Van der Flier, Ronald de Groot, Federico Martinon-Torres, Luregn J. Schlapbach, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Matthew R. Lewis, Michael Levin, Myra McClure & EUCLIDS consortium
Journal:
Publicación independiente
Impact factor
DTAP5-HBV-IPV-HIB PEDIATRIC HEXAVALENT COMBINATION VACCINE FOR USE IN CHILDREN FROM 6 WEEKS THROUGH TO 4 YEARS OF AGE.
Obando-Pacheco P, Rivero-Calle I, Raguindin PF, Martinón-Torres F.
Journal:
Expert Rev Vaccines
Publicación independiente
Impact factor
4.362
Q2
DIFFERENCES BETWEEN DIABETIC AND NON-DIABETIC PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA IN PRIMARY CARE IN SPAIN
Arias Fernández L, Pardo Seco J, Cebey-López M, Gil Prieto R, Rivero-Calle I, Martinon-Torres F, Gil de Miguel Á; NEUMOEXPERTOS group, Martinón-Torres F, Vargas D, Mascarós E, Redondo E, Díaz-Maroto JL, Linares-Rufo M, Gil A, Molina J, Ocaña D, Rivero-Calle I.
Journal:
BMC Infect Dis
Publicación independiente
Impact factor
2.688
Q3
DIAGNOSTIC CRITERIA FOR ACUTE FPIES: WHAT ARE WE MISSING?
Marta Vazquez-Ortiz, Laura Argiz, Adrianna Machinena, Luis Echeverria, Cristina Blasco, Ana Prieto, Sonsoles Infante, Leticia Vila, Emilio Garcia, Purificación Gonzalez-Delgado, SoniaVazquez-Cortes, Simona Barni, Frederico Martinon-Torres, BIO-FPIES study network
Journal:
J Allergy Clin Immunol Pract
Publicación independiente
Impact factor
IMMUNOGENICITY, TRANSPLACENTAL TRANSFER OF PERTUSSIS ANTIBODIES AND SAFETY FOLLOWING PERTUSSIS IMMUNIZATION DURING PREGNANCY:EVIDENCE FROM A RANDOMIZED, PLACEBO-CONTROLLED TRIAL
Kirsten P. Perrett, Scott A. Halperin, Terry Nolan, Cristina Martínez Pancorbo, Bruce Tapiero, Federico Martinón-Torres, Zbynek Stranak, Miia Virta, Otto G. Vanderkooi, Pavel Kosina, Maria Begoña Encinas Pardilla, Ignacio Cristobal García, Gian Vincenzo Zuccotti, Lusine Kostanyanm, Nadia Meyer, Maria Angeles Ceregido, Brigitte Cheuvart, Sherine O. Kuriyakose, Manuel Marcos Fernández, Miguel Ángel Rodríguez Zambrano, Adrián Martín García, Juan Eloy Asenjo de la Fuente, Maria Dolores Camacho Marín, María de la Calle Fernández-Miranda, Yolanda Romero Espinar, Paola Giovanna Marchisio, Paolo Manzoni, Narcisa Mesaros
Journal:
Vaccine
Publicación independiente
Impact factor
3.143
Q2
BIOSYNTHETIC HOMEOSTASIS AND RESILIENCE OF THE COMPLEMENT SYSTEM IN HEALTH AND INFECTIOUS DISEASE.
1Willems E, Alkema W, Keizer-Garritsen J, Suppers A, van der Flier M, Philipsen RHLA, van den Heuvel LP, Volokhina E, van der Molen RG, Herberg JA, Levin M,Wright VJ, Ahout IML, Ferwerda G, Emonts M, Boeddha NP, Rivero-Calle I, Torres FM, Wessels HJCT, de Groot R, van Gool AJ, Gloerich J, de Jonge MI.
Journal:
Ebiomedicine
Publicación independiente
Impact factor
5.736
Q1
Year:
2019
Doi:
IMPACT OF TETANUS-DIPHTHERIA-ACELLULAR PERTUSSIS IMMUNIZATION DURING PREGNANCY ON SUBSEQUENT INFANT IMMUNIZATION SERORESPONSES: FOLLOW-UP FROM A LARGE RANDOMIZED PLACEBO-CONTROLLED TRIAL
Kirsten P. Perrett, Scott A. Halperin, Terry Nolan, Alfonso Carmona Martínez, Federico Martinón-Torres, Jose García-Sicilia, Miia Virta , Otto G. Vanderkooi, Gian Vincenzo Zuccotti, Paolo Manzoni, Lusine Kostanyan, Nadia Meyer, Maria Angeles Ceregido, Brigitte Cheuvart , Sherine O. Kuriyakose l, Zbynek Stranak, Jose M. Merino Arribas, María José Cilleruelo Ortega, Mariano Miranda-Valdivieso, Begoña Arias Novas, Jose Tomas Ramos Amador, Felix Omeñaca, Manuel Baca, Paola Giovanna Marchisio, Narcisa Mesaros
Journal:
Vaccine
Publicación independiente
Impact factor
3.143
Q2
BACTEREMIA IN CHILDHOOD LIFE-THREATENING INFECTIONS IN URBAN GAMBIA: EUCLIDS IN WEST AFRICA
F Secka, J A Herberg, I Sarr, S Darboe, G Sey, M Saidykhan, M Wathuo, M Kaforou, M Antonio, A Roca, S M A Zaman, M Cebey-López, N P Boeddha, S Paulus, D S Kohlfürst, M Emonts, W Zenz, E D Carrol, R de Groot, L Schlapbach, F Martinon-Torres, K Bojang, M Levin, M van der Flier, S T Anderson on behalf of the EUCLIDS Consortium
Journal:
Open Forum Infectious Diseases
Publicación independiente
Impact factor
3.656
Q2
THE CHALLENGES OF INFLUENZA FOR PUBLIC HEALTH
Francisco Alvarez, Filipe Froes, Amos García Rojas, David Moreno-Perez & Federico Martinon-Torres
Journal:
Future Microbiol.
Publicación independiente
Impact factor
2.907
Q3
MENINGOCOCCAL GROUP B VACCINE FOR THE PREVENTION OF INVASIVE MENINGOCOCCAL DISEASE CAUSED BY NEISSERIA MENINGITIDIS SEROGROUP B
Rivero Calle, I; Raguindin PF; Gómez Rial, J; Rodríguez-Tenreiro, C; Martinón-Torres, F.
Journal:
Infection and Drug Resistance
Publicación independiente
Impact factor
2.984
Q1
A qPCR expression assay of IFI44L gene differentiates viral from bacterial infections in febrile children
Alberto Gómez-Carballa, Miriam Cebey-López, Jacobo Pardo-Seco, Ruth Barral-Arca, Irene Rivero-Calle, Sara Pischedda, María José Currás-Tuala1, José Gómez-Rial, Francisco Barros, Federico Martinón-Torres & Antonio Salas
Journal:
Sci Rep
Publicación independiente
Impact factor
PERSISTENCE OF THE IMMUNE RESPONSE AFTER 4CMENB VACCINATION, AND THE RESPONSE TO AN ADDITIONAL BOOSTER DOSE IN INFANTS, CHILDREN, ADOLESCENTS AND YOUNG ADULTS
Federico Martinón-Torres, Terry Nolan, Daniela Toneatto & Angelika Banzhoff
Journal:
Hum Vaccin Immunother
Publicación independiente
Impact factor
2.619
Q2
FALSE VACCINE CONTRAINDICATIONS AMONG HEALTHCARE PROVIDERS IN EUROPE: A SHORT SURVEY AMONG MEMBERS OF THE EUROPEAN SOCIETY OF PEDIATRIC INFECTIOUS DISEASES
Irene Rivero, Peter Francis Raguindin, Robb Buttler and Federico Martinon-Torres
Journal:
Pediatr Infect Dis J.
Publicación independiente
Impact factor
2.126
Q2
ASSOCIATION BETWEEN RESPIRATORY SYNCYTIAL VIRUS-ASSOCIATED ACUTE LOWER RESPIRATORY INFECTION IN EARLY LIFE AND RECURRENT WHEEZE AND ASTHMA IN LATER CHILDHOOD
Shi T, Ooi Y, Zaw EM, Utjesanovic N, Campbell H, Cunningham S, Bont L, Nair H, RESCEU Investigators. COLLABORATORS (Nair H, Campbell H, Shi T, Zhang S, Li Y, Openshaw P, Wedzicha J, Falsey A, Miller M, Beutels P, Bont L, Pollard A, Molero E, Martinon-Torres F, Heikkinen T, Meijer A, Fischer TK, Berge MVD, Giaquinto C, Mikolajczyk R, Hackett J, Cai B, Knirsch C, Leach A, Stoszek SK, Gallichan S, Kieffer A, Demont C, Cheret A, Gavart S, Aerssens J, Wyffels V, Cleenewerck M, Fuentes R, Rosen B.)
Journal:
J Infect Dis
Publicación independiente
Impact factor
5.022
Q1
Year:
2019
Doi:
USE OF THE WHO ACCESS, WATCH, AND RESERVE CLASSIFICATION TO DEFINE PATTERNS OF HOSPITAL ANTIBIOTIC USE (AWARE):AN ANALYSIS OF PAEDIATRIC SURVEY DATA FROM 56 COUNTRIES
Yingfen Hsia, Brian R Lee, Ann Versporten, Yonghong Yang, Julia Bielicki, Charlotte Jackson, Jason Newland, Herman Goossens, Nicola Magrini, Mike Sharland on behalf of the GARPEC and Global-PPS networks* (Federico Martinon-Torres)
Journal:
Lancet Glob Health.
Publicación independiente
Impact factor
21.597
Q1
Year:
2019
Doi:
CLINICAL PRESENTATION OF INFLUENZA IN CHILDREN 6 TO 35 MONTHS OF AGE: FINDINGS FROM A RANDOMIZED CLINICAL TRIAL OF INACTIVATED QUADRIVALENT INFLUENZA VACCINE
Jasur Danier, Luis Rivera, Carine Claeys, Ghassan Dbaibo, Varsha K. Jain, Pope Kosalaraksa, Wayne Woo, Emad Yanni, Khalequ Zaman, Beatriz Acosta, Arshad Amanullah, Miguel Ariza, Maria L. Arroba Basanta, Ashish Bavdekar, Alfonso Carmona, Luis Cousin, Adolfo Diaz, Javier Diez-Domingo, Ener C. Dinleyici, Saul N. Faust, Jose Garcia-Sicilia, Grace D. Gomez-Go, Maria L. A. Gonzales, Mustafa Hacimustafaoglu, Stephen M. Hughes, Allen Izu, Teresa Jackowska, Shashi Kant, Marilla Lucero, Josep Mares Bermudez, Federico Martinón-Torres, May Montellano, Roman Prymula, Thanyawee Puthanakit,Renata Ruzkova, Iwona Sadowska Krawczenko, Jyoti Soni, Henryk Szymanski, Angels Ulied, Anne Schuind and Bruce L. Innis for the Flu4VEC Study Group
Journal:
Pediatr Infect Dis J.
Publicación independiente
Impact factor
2.126
Q2
IMMUNOGENICITY OF THE PNEUMOCOCCAL NON-TYPEABLE HAEMOPHILUS INFLUENZAE PROTEIN D CONJUGATE VACCINE (PHID-CV) ADMINISTERED CONCOMITANTLY WITH THE MENINGOCOCCAL SEROGROUP B (4CMENB) VACCINE IN INFANTS: A POST-HOC ANALYSIS IN A PHASE 3B, RANDOMISED, CONTROLLED TRIAL
Marco Aurelio P. Safadi, Federico Martinon-Torres, Lily Yin Weckx, Edson Duarte Moreira Junior, Eduardo Jorge da Fonseca Lima, Arnold Willemsen, Daniela Toneatto, Md Ahsan Habib, Dorota Borys
Journal:
Vaccine
Publicación independiente
Impact factor
3.143
Q2
ANCESTRY PATTERNS INFERRED FROM MASSIVE RNA-SEQ DATA
Barral-Arca, R; Pardo-Seco, J; Bello, X; Martinon-Torres, F; Salas, A
Journal:
RNA
Publicación independiente
Impact factor
4.320
Q2
THE RESVINET SCORE FOR BRONCHIOLITIS: A SCALE FOR ALL SEASONS
Justicia-Grande, AJ; Martinon-Torres, F
Journal:
Am J Perinatol
Publicación independiente
Impact factor
1.474
Q3
TIPICO IX: REPORT OF THE 9TH INTERACTIVE INFECTIOUS DISEASE WORKSHOP ON INFECTIOUS DISEASES AND VACCINES
Federico Martinón-Torres, Xavier Bosch, Rino Rappuoli, Shamez Ladhani, Esther Redondo, Timo Vesikari, Adolfo García-Sastre, Irene Rivero-Calle, José Gómez-Rial, Antonio Salas, Carlos Martín, Adam Finn & Robb Butler
Journal:
Hum Vaccin Immunother
Publicación independiente
Impact factor
2.619
Q2
PERTUSSIS VACCINATION DURING PREGNANCY: A MULTI-COUNTRY RANDOMISED PLACEBO-CONTROLLED TRIAL ASSESSING IMMUNOGENICITY AND SAFETY OF DTPA IN MOTHERS AND THEIR INFANTS
Perrett, K; Garcia, IC; Halperin, S; Nolan, T; Virta, M; Stranak, Z; Surico, D; Kostanyan, L; Ceregido, MA; Kuriyakose, S; Cheuvart, B; Meyer, N; Pancorbo, CM; Fernandez, MM; Martinon-Torres, F; Zambano, MAR; Vanderkooi, O; Kosina, P; Garcia, AM; Pardilla, MBE; Marin, MDC; de la Fuente, JFA; Fernandez-Miranda, MD; Splinter, K; Espinar,; Zuccotti, GV; Marchisio, PG; Manzoni, P; Mesaros, N
Journal:
Bjog-an international journal of obstetrics and gynaecology
Publicación independiente
Impact factor
4.663
Q1
THE NEW OFFICIAL VACCINE CALENDAR FOR ADULTS DOES NOT INCLUDE THE PREVENTION OF PNEUMOCOCCAL PNEUMONIA
Redondo, E; Rivero-Calle, I; Mascaros, E; Diaz-Maroto, JL; Linares, M; Gil, A; Molina, J; Jimeno, I; Ocana, D; Yuste, JE; Martinon-Torres, F
Journal:
Rev Esp Quimioter
Publicación independiente
Impact factor
1.132
Q4
Year:
2019
Doi:
THE CHALLENGE OF THE LABORATORY DIAGNOSIS IN A CONFIRMED CONGENITAL ZIKA VIRUS SYNDROME IN UTERO: A CASE REPORT.
1. Sulleiro E , Frick MA , Rodó C , Espasa M , Thorne C , Espiau M , Martín-Nalda A , Suy A , Giaquinto C , Melendo S , Rando A , Alarcón A , Martinón-Torres F , Pumarola T , Soler-Palacín P , Soriano-Arandes A .
Journal:
Medicine (Baltimore)
Publicación independiente
Impact factor
1.868
Q3
No results found.
¿Respetamos los derechos del niño?
A. Rodríguez Núñez, M.ªE. Perea Rodríguez, F. Martinón Torres
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
Proteína C activada humana recombinante en el tratamiento de niños con púrpura fulminante meningocócica
F. Martinón-Torres, J.M.ª Iglesias Meleiro, M. Fernández Sanmartín, A. Rodríguez Núñez, J.M.ª Martinón Sánchez
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
Información y atención en cuidados intensivos pediátricos. Opiniones de los padres
A. Rodríguez Núñez, P. Crespo Suárez, C. Martins de Oliveira Pereira Caldas, M.ªT. Pérez Rodríguez, F. Martinón Torres, J.M.ª Martinón Sánchez
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
VENTILACIÓN NO INVASIVA CON HELIOX APLICADA A LACTANTES
Martinón-Torres F, Crespo Súarez PA, Moliní Menchón N, Fernández Sanmartín M, Rodríguez Núñez A, Iglesias Meleiro JM, Redondo Collazo L
Doi:
An Pediatr
Factor de impacto:
Q4
Doi:
Cardiac Aspergillosis with Pedunculated Mass in the left ventricle
Rubio Alvarez J, Sierra Quiroga J, Rubio Taboada C, Fernandez Gonzalez A, Martinon Torres F, Garcia-Bengochea J.
Doi:
Tex Heart Inst J
Factor de impacto:
Q4
Doi:
Cambio de actitudes respecto al uso de casco en bicicleta después de sufrir un accidente grave
M. Fernández Sanmartín, P. Cabanas Rodríguez, M. Granero Asencio, E. Saavedra Chaves, L. Martínez Pérez, M.I. Berdullas Rodríguez, M.J. Otero Ferreiro, F. Martinón Torres, A. Rodríguez Núñez
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
Renovación Generacional
Martinón-Torres F
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
Ventilación mecánica en la bronquiolitis
A. Rodríguez Núñez, F. Martinón Torres, J.M.ª Martinón Sánchez
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
Ventilación de alta frecuencia
Martinón-Torres F, Ibarra de la Rosa I, Fernández Sanmartín M, García Menor E, Marinón Sánchez JM
Doi:
An Pediatr (Barc)
Factor de impacto:
Q4
Doi:
Agudización grave del asma
F. Martinón-Torres, M. Fernández Sanmartín, E. Saavedra Chaves, M. Granero Asencio, J.M.ª Martinón Sánchez
Doi:
An Pediatr
Factor de impacto:
Q4
Doi:
MAPPING GENOME VARIATION OF SARS-COV-2 WORLDWIDE HIGHLIGHTS THE IMPACT OF COVID-19 SUPER-SPREADERS
Alberto Gómez-Carballa, Xabier Bello, Jacobo Pardo-Seco, Federico Martinón-Torres, Antonio Salas
bioRxiv
Factor de impacto:
Q1
Doi:
CLINICAL CHARACTERISTICS OF 58 CHILDREN WITH A PEDIATRIC INFLAMMATORY MULTISYSTEM SYNDROME TEMPORALLY ASSOCIATED WITH SARS-COV-2
Elizabeth Whittaker; Alasdair Bamford; Julia Kenny; Myrsini Kaforou; Christine E. Jones; Priyen Shah; Padmanabhan Ramnarayan; Alain Fraisse; Owen Miller; Patrick Davies; Filip Kucera; Joe Brierley; Marilyn McDougall; Michael Carter; Adriana Tremoulet; Chisato Shimizu Jethro Herberg; Jane C. Burns; Hermione Lyall; Michael Levin; for the PIMS-TS Study Group and EUCLIDS and PERFORM Consortia (Federico Martinón-Torres)
JAMA
Factor de impacto:
Q1
Doi:
RNA-SEQ DATA-MINING ALLOWS THE DISCOVERY OF TWO LONG NON-CODING RNA BIOMARKERS OF VIRAL INFECTION IN HUMANS
Ruth Barral-Arca, Alberto Gómez-Carballa, Miriam Cebey-López, María José Currás-Tuala, Sara Pischedda, Sandra Viz-Lasheras, Xabier Bello, Federico Martinón-Torres and Antonio Salas
International J Molecular Sciences
Factor de impacto:
Q1
Doi:
COST OF RESPIRATORY SYNCYTIAL VIRUS-ASSOCIATED ACUTE LOWER RESPIRATORY INFECTION MANAGEMENT IN YOUNG CHILDREN AT THE REGIONAL AND GLOBAL LEVEL: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Zhang S, Akmar LZ, Bailey F, Rath BA, Alchikh M, Schweiger B, Lucero MG, Nillos LT, Kyaw MH, Kieffer A, Tong S, Campbell H, Beutels P, Nair H; RESCEU Investigators
J Infect Dis.
Factor de impacto:
Q1
Doi:
IMMUNOLOGICAL AND INFLAMMATORY BIOMARKERS OF SUSCEPTIBILITY AND SEVERITY IN ADULT RESPIRATORY SYNCYTIAL VIRUS INFECTIONS.
Wiseman DJ, Thwaites RS, Drysdale SB, Janet S, Donaldson GC, Wedzicha JA, Openshaw PJ; RESCEU Investigators
J Infect Dis.
Factor de impacto:
Q1
Doi:
LOW SENSITIVITY OF BINAXNOW RSV IN INFANTS.
Zuurbier RP, Bont LJ, Langedijk AC, Hamer M, Korsten K, Drysdale SB, Snape MD, Robinson H, Pollard AJ, Martinón-Torres F, Rodríguez-Tenreiro Sánchez C, Gómez-Carballa A, Dacosta-Urbieta AI, Heikkinen T, Cunningham S, van Houten MA, Wildenbeest JG; RESCEU Investigators .
J Infect Dis.
Factor de impacto:
Q1
Doi:
PROTECTING THE MOST VULNERABLE AGE GROUP: A REVIEW OF MENACWY-TT IMMUNOGENICITY AND SAFETY IN INFANTS.
Martinón-Torres F, Serra L, Safadi MAP.
Expert Rev Vaccines
Factor de impacto:
Q2
Doi:
PATHWAY TOWARDS AN IDEAL AND SUSTAINABLE FRAMEWORK AGREEMENT FOR THE PUBLIC PROCUREMENT OF VACCINES IN SPAIN: A MULTI-CRITERIA DECISION ANALYSIS.
Zozaya González N, Alcalá Revilla B, Arrazola Martínez P, Chávarri Bravo JR, Cuesta Esteve I, García Rojas A, Martinón-Torres F, Redondo Margüello E, Rivero Cuadrado A, Tamames Gómez S, Villaseca Carmena J, Hidalgo-Vega A
Hum Vaccine Immunother
Factor de impacto:
Q2
Doi:
WHOLE-EXOME SEQUENCING FOR THE IDENTIFICATION OF RARE VARIANTS IN PRIMARY IMMUNODEFICIENCY GENES IN CHILDREN WITH SEPSIS - A PROSPECTIVE POPULATION-BASED COHORT STUDY
Alessandro Borghesi, Johannes Trück, Samira Asgari, Vanessa Sancho-Shimizu, Philipp KA Agyeman, Evangelos Bellos, Eric Giannoni, Martin Stocker, Klara M Posfay-Barbe, Ulrich Heininger, Sara Bernhard-Stirnemann, Anita Niederer-Loher, Christian R Kahlert, Giancardlo Natalucci, Christa Relly, Thomas Riedel, Claudia E Kuehni, Christian W. Thorball, Nimisha Chaturvedi, Federico Martinon-Torres, Taco W Kuijpers, Lachlan Coin, Victoria Wright, Jethro Herberg, Michael Levin, Christoph Aebi, Christoph Berger, Jacques Fellay, Luregn J Schlapbach, for the EUCLIDS consortium and the Swiss Paediatric Sepsis Study
Clin Infect Dis
Factor de impacto:
Q1
Doi: